Choose an Option:
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Upload two aligned fasta files of your own. See an example of what input files should look like here. Also select the correct taxonomic group for your files and input the name of the model species exactly as it occurs in its header line in your files. The model species will determine which protein from your files we will base residue positions on. After the algorithm has finished, a heat map and csv file will be made available for download. The highest score, chance of interaction, and location of interaction will be noted. More information about the algorithm and mutual information in general can be found on the "about" page. Depending on the size of your input files, the algorithm could take up to a minute to complete.
If you wish to see example input and output, click "Run Example".
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Search and select a pair of proteins from our database to see their highest score, their chance of interaction, and the locations at which the highest interaction scores occur. Note that our database is not fully connected so the list of possibilities for the second protein will update according to what you select for the first. You may download all interactions here.
